Isotope Standards
Medchemexpress LLC p,p'-DDE-d8 | 93952-19-3 | 99% | 5 MG
p,p'-DDE-d8 is the deuterium labeled p,p'-DDE. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethylene (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM. It is for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Sigma Aldrich Fine Chemicals Biosciences Benzoyl chloride-d5 99 atom % D | 43019-90-5 | MFCD00134309 | 1G
Benzoyl chloride-d5 99 atom % D | Purity: 99% (CP) | Mol Wt: 145.6 | 43019-90-5 | MFCD00134309 | 1G
Medchemexpress LLC Levofloxacin-d8 ((-)-ofloxacin-d8) | 1217716-71-6 | 99.8% | 1 MG
Levofloxacin-d8 is a deuterium-labeled version of Levofloxacin. Levofloxacin is a synthetic fluoroquinolone that acts as an antibacterial agent by inhibiting the supercoiling activity of bacterial DNA gyrase, thereby halting DNA replication.
- Deuterium labeled levofloxacin
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- For research use only
eMolecules Medchem Express / Enalaprilat-d5 / 1mg / 415688613 / HY-B0231AS / / 349554-00-3 / MFCD06656364 / 353.430 / C18H24N2O5
Medchem Express / Enalaprilat-d5 / 1mg / 415688613 / HY-B0231AS / / 349554-00-3 / MFCD06656364 / 353.430 / C18H24N2O5
Medchemexpress LLC Sumatriptan-d6 succinate | 1215621-31-0 | 99.6% | 1 MG
Sumatriptan-d6 succinate is a deuterium-labeled version of Sumatriptan succinate. It functions as an orally active 5-HT1 receptor agonist, targeting 5-HT1D, 5-HT1B, and 5-HT1A receptors. This compound is valuable for research involving migraine headaches, where deuterium substitution can impact drug pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
eMolecules Medchem Express / Hydroxyzine D8 / 1mg / 533803403 / HY-B0548S1 / / 1189480-47-4 / MFCD09840787 / 382.960 / C21H27ClN2O2
Medchem Express / Hydroxyzine D8 / 1mg / 533803403 / HY-B0548S1 / / 1189480-47-4 / MFCD09840787 / 382.960 / C21H27ClN2O2
Medchemexpress LLC Dasatinib-d8 | 1132093-70-9 | MFCD15071210 | 99.2% | 496.05 g/mol | C22H18D8ClN7O2S | 1 MG
Dasatinib-d8 is a deuterium-labeled analogue of dasatinib supplied as a high-purity reference standard for analytical and research use, primarily as an internal standard for quantitative mass spectrometry. It is intended for method development, validation, and stability studies where isotopic labeling improves accuracy and precision (CAS 1132093-70-9).
- Deuterium-labeled internal standard for mass spectrometry applications.
- High purity for reliable quantification and reproducible results.
- Suitable for LC-MS and GC-MS method development and validation.
- Soluble in DMSO at high concentration for convenient stock preparation.
- Packaged for analytical reference and stability testing.
Medchemexpress LLC Dabigatran-d4 hydrochloride | 00-00-0 | ≥98.0% | 512.00 | C25H22D4ClN7O3 | 10 MG
Dabigatran-d4 hydrochloride is a deuterium-labeled analogue of dabigatran provided as the hydrochloride salt. It is intended for use as a tracer and internal standard in quantitative analytical workflows; the parent scaffold is a reversible, selective direct thrombin inhibitor with a reported Ki of 4.5 nM.
- Deuterium-labeled for accurate mass spectrometry quantitation.
- Suitable as internal standard for NMR, GC-MS, and LC-MS analyses.
- High purity (≥98.0%) for reliable analytical performance.
- Hydrochloride salt form improves handling and stability.
- Supports tracer studies and quantitative method development.
Medchemexpress LLC Aminobenzenesulfonic auristatin E-d8 | 00-00-0 | MFCD34676922 | 98.0% | C37H56D8N6O8S | 10MG
Aminobenzenesulfonic auristatin E-d8 is a deuterium-labeled drug-linker reagent used in antibody-drug conjugate (ADC) research. It combines auristatin E with an aminobenzenesulfonic linker and is supplied as a solid for preclinical, analytical, and linker-optimization studies. It is intended for research use only.
- Deuterium-labeled version of auristatin E for tracer and stability studies.
- High purity (98.0%).
- Chemical formula: C37H56D8N6O8S.
- Molecular weight: 761.05.
- White to off-white solid appearance.
- Storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
- Supplied in milligram-scale quantities suitable for ADC development and analytical work.
Medchemexpress LLC Bortezomib-d8 | 00-00-0 | MFCD09056737 | 98.0% | 392.29 g/mol | C19H17D8BN4O4 | 1 MG
Bortezomib-d8 is the deuterium-labeled (d8) isotopologue of bortezomib, a reversible and selective 20S proteasome inhibitor used in research on proteasome function, apoptosis, and multiple myeloma. It is supplied as a high-purity analytical reagent for use in mass spectrometry, tracer studies, and mechanistic experiments.
- Deuterium-labeled analogue for use as an internal standard.
- High purity suitable for analytical applications.
- Optimized for mass spectrometry and quantitative assays.
- Small package size for low-quantity, high-value experiments.
- Stable isotope labeling aids in accurate tracer and mechanistic studies.
eMolecules Medchem Express / NNK-d4 / 1mg / 784543856 / HY-126477S / / 764661-24-7 / MFCD01861565 / 211.257 / C10H13N3O2
Medchem Express / NNK-d4 / 1mg / 784543856 / HY-126477S / / 764661-24-7 / MFCD01861565 / 211.257 / C10H13N3O2